KMID : 0356919820150010020
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Korean Journal of Anesthesiology 1982 Volume.15 No. 1 p.20 ~ p.24
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The Effects of Nitrous oxide-Nareotic Anesthesia and Surgery on Plasma Aldosterone Level
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Sohn IJ
Shin JC
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Abstract
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This study was performed to investigate the effects of nitrous oxide-narcotic anesthesia (Nitrous oxide-pethidine HCI-muscle relaxant) and surgery on plasma aldosterons level in surgical patients and the aldosterone level in plasma was measured by the Abbott Laboratorie¡¯s Aldosterone RIA Kit. Average body weights and ages of subjects were 58.1+/-6.45(kg) and 43.8+/-11.55(yrs) respectively. Mean control aldosterone level in plasma was 121.3+/-58.66I(pg/ml) (mean +/- SE) but it gradually rose during anesthesia and surgery. The mean plasma aldosterone level rose to 232.7+/-40.06(pg/ml) (p<0.005) at 90 minutes after the start of surgery, and therefore, it was a significantly higher value than that of the control.
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